In one ampoule (3 ml) contains:
Thiamine hydrochloride 100 mg;
Pyridoxine hydrochloride 100 mg;
Cyanocobalamin 1 mg
Included in the ingredients of Trivitron, the combination B vitamins affects a number of processes occurring in the body.This group Vitamins are part of enzymes that catalyze the reactions metabolism of carbohydrates, lipids and proteins.The combination of this group Vitamins in the preparation composition promotes the normalization of metabolism autonomic (vegetative) centers, formation processes, the momentum transfer and trophic function of neurons, improves the functioning of nerve cells and subcortical centers.
Vitamin B1 (thiamine nitrate) after resorption in the body turns into in thiamine pyrophosphate, which is a cofactor enzymes involved in the decarboxylation of pyro racemic acid and alpha keto glutamic acid. Thiamine is involved in carbohydrate and energy metabolism, especially in the nervous and muscular tissues, influences on the processes of excitation in synapses and in the fat, protein and water-salt metabolism, and during the synthesis of acetylcholine.
Vitamin B6 (pyridoxine hydrochloride) plays an important role in the metabolism. It is necessary for normal functioning of central and peripheral nervous system.When the body it is phosphorylated, turn into a pyridoxal-5-phosphate and is part of the enzymes that carry decarboxylation and transamination of amino acids.Pyridoxine is involved in the protein metabolism and synthesis of neurotransmitters, in the metabolism of tryptophan, methionine, cysteine, glutamic and other amino acids. It is of great importance in the histamine metabolism, in the processes of lipid metabolism, improves the liver function and nerve fibers, lipid metabolism in the atherosclerosis.
Vitamin B12 (cyanocobalamin) in the body is converted into kobamamid being the active form of vitamin B12. It has high biological activity. It is growth factor essential for normal blood formation and maturation of erythrocytes,takes part in the synthesis of instable (labile) methyl groups and the formation of choline, methionine, creatinine, nucleic acids.It contributes to the accumulation of compounds containing sulfgidrile group in erythrocytes, increasing their tolerance to the hemolysis.It activates the metabolism of carbohydrates and lipids, reduces the cholesterol level (Chemical shift) in atherosclerosis, and increases the lecithin/cholesterol index. It has a beneficial effect on the function of liver and nervous system, improves the tissuesregeneration.
•Nonspecific and degenerative diseases of peripheral nerves -neuritis, the different etiology polinevrit (alcohol, post-infectious, toxic, diabetic), neuralgia, paresthesia, peripheral paralysis,polyneuropathy,asthenia,encephalopathy,encephalopathy,osteochondritis,lumbago,sciatica,arthralgia and myosalgia (myalgia), myasthenia, neuroculatory dystonic
•Spastic condition of central genesis, traumatic lesions of general nervous system, vegetative neurosis, trochaic, Wernicke's encephalopathy.
•Dermatitis (neuro gene origin), seborrheic and not seborrheic piodermia, eczema, psoriasis, shingles, exudative diathesis, acne and other.
•Degenerative processes in the retina, glaucoma, diabetic retinopathy, macular degeneration (macular dystrophy), optic neuritis, toxic disorder to the optic nerve.
•Peptic gastric ulcer and duodenal ulcer, gastritis, duodenitis, cholecystitis, pancreatitis, chronic cholecystitis, hepatitis, hepatic cirrhosis.
Hypersensitivity to vitamin B1, B6 or B12.
The preparation is contraindicated for children under 12 years.
Rarely, allergic reactions. In some cases, there is a sense of anxiety.
Common symptoms are sudden: sweating, feeling of weakness, dizziness.
Use in pregnancy and lactation.Clinical studies of the preparation on animals or on pregnant women were not conducted. Vitamin B6 is excreted into breast milk through the placental barrier.
Ability to influence on reaction rate while driving and operating other machines.Clinical studies of the preparation influence on velocity reactions while driving motor transport and operating other mechanisms have not been conducted.
- No,experiencewith usethispreparationinchildren.
Due to the lack of studies regarding the compatibility with medicines, Trivitron in the form solution for injection should not be mixed with other medicaments.
In severe disease course, the dose for adults is: in the beginning of the application to 3 ml R-RA (content of 1 mg in/m or every day to reduce the pain symptoms; in the future - 3 ml 1-2 times a week.
At disease of moderate severity, the dose for adults is 3 ml 1-2 times a week.
Preparation is administered intramuscularly in the upper outer quadrant of the gluteus muscle.
Duration of treatment depends on the nature and course of the disease and is determined by the doctor.
Solution for intramuscular injection in vials 3 ml, five vials- in a box