COMPOSITION: Each tablet contains Magnesium (magnesium aspartate) 10 mg, Manganese 1 mg, DimethylglycineHCl 250 mg, Glutamine 200 mg, Acetyl-L-Carnitine 175 mg, Fosfotidilserina (soy) 100 mg of phosphatidylcholine (soy-bean) 50 mg.
Active ingredients of Neurophola play a key physiological role in the work of nervous cells, they have membrane-protective effect, restore the structure of the nervous tissue, improve metabolism of brain cells and thereby reduce the risk of growth of cognitive dysfunctions associated with aging, primarily - memory and attention concentration impairment, as well as limit the area of damage during various metabolic disorders, reduces the damaging effect of hypoxic conditions.
Active components of Neurophol are structural elements of the nerve cells and brain tissues and regulate the formation of neurotransmitters. Product restores changed phospholipid composition of neuronal membranes thanks to phosphatidylcholine and Phosphatidylserine, improves the plasticity of neuronal membranes, receptors function and synaptic transmission, enhances the metabolic processes in the central nervous system, improves cerebral blood flow, enables the formation of the reticular structure of the brain. Neurophol in patients with ischemic stroke (in the early recovery period) has a normalizing effect on the affected and, in particular, compensatory brain areas. Neurophol also has positive effects on cognitive and behavioral reactions, activates mental activity, improves attention concentration and memory, and information reproduction, improves mood, helps eliminate emotional instability,irritability and apathy in patients with vascular diseases of the brain (dyscirculatory, encephalopathy, residual effects of cerebrovascular accident) and involutivepsychoorganic syndrome. Phospholipids as a structural material are also able to prevent the development of ischemic stroke due to the replacement of damaged lipids, such as oxidized lipids. Acetyl-L-carnitine causes application of Neurophola in neurometabolic therapy of ischemic brain tissues in order to reduce the severity of the consequences of tissue hyposcopy, to improve microcirculation state, activation of energetic metabolism. Use of Acetyl L-carnitine is accompanied with the activation of the neuroprotective mechanisms, in particular, with the increase of synthesis of nerves growth factor and tyrosine kinase A, which provides an increase in phosphorylation of extracellular signal-regulated kinase and enhances cell survival.Neurophol is involved in the formation of neurotransmitters, improves the metabolism of brain tissue in patients with chronic disorders of cerebral circulation, particularly circulatory encephalopathy, vertebrobasilar insufficiency, improves cognitive function. On the background of the drug use facts about improvement of abstract and concrete thinking, memory are stated. Neurophol also regulates nitrogen balance, prevents the toxic effects of ammonia compounds, preventing their accumulation and shows strong antioxidant effect on the body.
Thanks to dimethylglycineNeurophol has the ability to bind homocysteine, which is potent pro-inflammatory agent and inducer of the formation of free radicals.
Methyl groups, in addition to DNA repair and neutralization of homocysteine, perform a variety of useful functions in the body: detoxification, stimulation of serotonin synthesis, improving of neurotrophic functions of the brain, activation of leukocytes and growth of immunity, stimulation of protein synthesis and reparative processes in tissues, membrane-protective.
• Ischemic hypoxia
• Prevention of cognitive impairment.
• Chronic disorder of cerebral circulation.
• The period of rehabilitation after stroke
• Somatogenic and intoxication psychosis
• Mental exhaustion
• The consequences of meningitis and encephalitis, encephalopathy
• Progressive myopathy
• Reactive depressive state
• Mental retardation
• Cerebral Palsy
• Consequences of generic intracranial injury
• Parkinson's disease
• Alzheimer's Disease
• Down's syndrome
• Cerebrovascular Dementia
• Peripheral neuropathy of various etiologies ( radicular , stem , inflammatory , mechanical)
• Primary and secondary involution syndromes on the background of vascular encephalopathies
• Reduction of mental capacity, for improvement of memory and attention concentration
• Age-related dementia
• Multiple Sclerosis
• Chronic Fatigue Syndrome
• emotional stress and harmful addictions .
• Asthenia , muscular dystrophy
• The syndrome of anorexia nervosa
Contraindications: idiosyncrasy to the components of the drug, epilepsy, cirrhosis with liver failure.
Side effects: Some components of the drug is well tolerated . In extremely rare cases nausea and an allergic reaction that don’t require discontinuation of therapy may be noted
Use during pregnancy and lactation: Pregnant and lactating mothersshould consult a doctor before use.
Doses and application rules:
The average therapeutic dose is:
for adults and children from 12 years: 1 tablet 2-3 times a day ;
for children from 6 to 12 years : 1 tablet 1-2 times a day ;
for children 3 to 6 years : ½ tablet 1-2 times a day . The course of treatment is determined by the doctor depending on the severity of the disease. For maintenance therapy the dose is adjusted individually.
Form: Tablets No 30