LISATHYONE

Glutathione 600mg/3ml
ATX Code: V03AB32(Glutathione)
Pharmacotherapeutic group: Detoxifying agent
Pharmachologic effect: Glutathione is a linear tripeptide with a sulfhydryl group, which includes L-glutamine,
L-cysteine ​​and glycine. It plays an important function in protecting body cells, being a strong antioxidant. There is a shortage in the human body
glutathione leads to the occurrence of many diseases, such as Parkinson's disease, type I tyrosinemia, alcohol poisoning and others.
In vivo and in vitro experiments have shown that glutathione deficiency can lead to mitochondrial damage and cell death caused by
an increase in the number of toxic forms of oxygen, leading to an increase in the number of free radicals.

Pharmacokinetics
15 minutes after an intravenous infusion of 2 g of glutathione, the average concentration of glutathione 
in the blood is 444 mmol/L (the average physiological concentration of glutathione in the blood is 6.9 mmol/L).
Distribution volume - 15 l. The half-life is 10 minutes. Clearance - 850 ml/min. Excreted in urine unchanged or as cysteine ​​90 minutes after infusion.

Dosage regimen
For intravenous administration, the contents of the bottle are dissolved in 250-500 ml of 0.9% sodium chloride solution.
The drug solution is used immediately after preparation; reuse of the remaining solution is not allowed.
For severe forms of hepatitis of various etiologies - 1.2-2.4 g intravenously per day for 30 days in the form of infusions. 
For alcoholic hepatitis - 1.8 g intravenously per day for 14-30 days in the form of infusions. For alcoholic cirrhosis, 
1.2 g intravenously per day for 30 days as an infusion. For hepatic steatosis - 1.8 g intravenously per day for 30 days in the form of infusions.

Contraindications for use
· childhood;
· individual intolerance to the components of the drug.
With caution: old age (the drug should be prescribed
in reduced doses with careful monitoring of the condition).

Terms of sale
On prescription.

Name and address of the organization receiving complaints (suggestions) regarding the quality of medicines: 
Representative office of “Delotta LTD” Tashkent, Mirabad district, Afrosiab street 4 B, office 307 A. Phone +998712059900
Manufacturer: Laboratorio Italiano Biochimico Farmaceutico Lisapharma S.P.A. ViaLicinio 11 – 22036 Erba (Co) – Italy